About Us
Description
The Undiagnosed Diseases Network (UDN) is a research study funded by the National Institutes of Health. Its purpose is to bring together clinical and research experts from across the United States to solve the most challenging medical mysteries using advanced technologies.
Through this study, we hope to both help individual patients and families living with the burden of undiagnosed diseases, and contribute to the understanding of how the human body works.
Sites
The UDN is made up of a Data Management Coordinating Center, Clinical Sites, and Core Facilities.
The Data Management Coordinating Center, which coordinates the work of the UDN, is based at Harvard Medical School, Morehouse School of Medicine, Stanford University, University of Alabama at Birmingham, University of Utah, and Washington University in St. Louis.
The Clinical Sites, where UDN participants are evaluated, are located across the United States:
| Site | Location | Current Status |
|---|---|---|
| Baylor College of Medicine | Houston, TX | Open to new case submissions |
| Children’s Hospital of Philadelphia (CHOP) and University of Pennsylvania | Philadelphia, PA | Closed to new case submissions |
| Cincinnati Children’s Hospital | Cincinnati, OH | Opening to internal referrals soon |
| Duke University | Durham, NC | Open to new case submissions |
| Harvard affiliated hospitals (Boston Children’s Hospital, Brigham and Women’s Hospital, and Massachusetts General Hospital) | Boston, MA | Closed to new case submissions |
| Icahn School of Medicine at Mount Sinai | New York, NY | Open to new case submissions |
| Indiana University | Indianapolis, IN | Open to new case submissions |
| Johns Hopkins University | Baltimore, MD | Opening to internal referrals soon |
| Lurie Children’s Hospital | Chicago, IL | Opening to internal referrals soon |
| Mayo Clinic | Rochester, MN | Open to internal referrals only |
| Medical College of Wisconsin and Children’s Wisconsin | Milwaukee, WI | Open to internal referrals only |
| National Institutes of Health (NIH) Undiagnosed Diseases Program (UDP) | Bethesda, MD | Open to new case submissions |
| Sanford Health | Sioux Falls, SD | Open to internal referrals only |
| Stanford University | Palo Alto, CA | Open to new case submissions |
| University of Alabama at Birmingham | Birmingham, AL | Open to new case submissions |
| University of California, Irvine and Children’s Hospital of Orange County | Orange County, CA | Open to new case submissions |
| University of California, Los Angeles | Los Angeles, CA | Closed to new case submissions |
| University of Miami | Miami, FL | Open to new case submissions |
| University of Utah | Salt Lake City, UT | Closed to new case submissions |
| University of Washington and Seattle Children’s Hospital | Seattle, WA | Open to new case submissions |
| University of Wisconsin–Madison | Madison, WI | Opening to internal referrals soon |
| Vanderbilt University Medical Center | Nashville, TN | Open to new case submissions |
| Washington University | St. Louis, MO | Open to new case submissions |
| Yale University | New Haven, CT | Open to new case submissions |
At the Clinical Sites, doctors and healthcare providers, like neurologists, immunologists, nephrologists, endocrinologists, and geneticists, work together to help find the cause of participant symptoms.
The Sequencing Core, which provides sequencing services for the UDN, is at Baylor College of Medicine.
The Model Organisms Screening Center, located at Baylor College of Medicine, Washington University in St. Louis, and University of Oregon, helps the network understand how specific genetic changes contribute to disease by studying these changes in other organisms. The Metabolomics Core, located at the Mayo Clinic in Rochester, MN, provides metabolomics and experimental design consultation, laboratory analysis, and computational expertise to the UDN.
Reports
UDN Quarterly Report – Winter 2025UDN Quarterly Report – Fall 2024
UDN Quarterly Report – Summer 2024
UDN Quarterly Report – Spring 2024
UDN Quarterly Report – Winter 2024
UDN Quarterly Report – Fall 2023
UDN Quarterly Report – Summer 2023
UDN Quarterly Report – Spring 2023
UDN Quarterly Report – Winter 2023
UDN Quarterly Report – Fall 2022
UDN Quarterly Report – Summer 2022
UDN Quarterly Report – Spring 2022
UDN Quarterly Report – Winter 2022
UDN Quarterly Report – Fall 2021
UDN Quarterly Report – Summer 2021
UDN Quarterly Report – Spring 2021
UDN Quarterly Report – Winter 2021
UDN Quarterly Report – Fall 2020