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Our Current Research

Model Organisms

The Model Organisms Screening Center (MOSC) for the Undiagnosed Diseases Network (UDN) is composed of two Centers that use fruit fly (Drosophila melanogaster), nematode worm (Caenorhabditis elegans) and zebrafish (Danio rerio) genetics and biology to tackle rare and undiagnosed diseases.

Genes of interest

ETFDH WRNIP1 PRDM16 PIK3CD MED13L BSN

Meet Our Participants


26 weeks into the pregnancy, the participant was found to have intrauterine growth restriction (IUGR). She was born early at 34 weeks weighing 3 pounds and was fed through a G-tube as an infant. As she has grown up, she continues to be very small for her age and gaining … read more

Born at 37 weeks, the participant was initially healthy with the exception of jaundice and respiratory distress at birth. However, at 3 years old, he stopped meeting his growth milestones despite eating well. At that point, he was diagnosed with stomach muscle weakness (gastroparesis) and had a GJ tube placed. … read more

The participant was born after a pregnancy complicated by low amniotic fluid levels. He was delivered via c-section due to decreasing fetal heart rate. After birth, he was noted to be healthy. Concerns regarding his development arose at 6 months of age from his daycare providers. He has since continued … read more

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