Every year hundreds of patients face uncertainty when healthcare providers are unable to discover the cause for their symptoms.
The Undiagnosed Diseases Network (UDN) is a research study backed by the National Institutes of Health that seeks to provide answers for patients and families affected by these mysterious conditions.
Model Organisms
The Model Organisms Screening Center (MOSC) for the Undiagnosed Diseases Network (UDN) is composed of two Centers that use fruit fly (Drosophila melanogaster), nematode worm (Caenorhabditis elegans) and zebrafish (Danio rerio) genetics and biology to tackle rare and undiagnosed diseases.
Publications

The participant was delivered via C-section at 35 weeks gestation. The pregnancy was complicated by persistent nausea and vomiting (hyperemesis gravidarum), as well as decreased fetal movements. In early infancy, she exhibited sweating with feeding which led to the detection of an irregular heartbeat (Wolff-Parkinson-White syndrome), which was treated with … read more

The participant was delivered via C-section due to breech presentation. She was noted to have decreased fetal movements during the pregnancy. At birth, the participant had a good Apgar score but did not cry well. She rarely cried during infancy. Rather than being fed on demand, the participant was fed … read more

The participant was born prematurely at 33 weeks after she was diagnosed with IUGR at 27 weeks. She had a gap between her larynx and esophagus (laryngeal cleft) which was later repaired. During infancy, she experienced episodes of retching and choking, which lead to low blood oxygen levels and occasionally … read more
