The Undiagnosed Disease Network (UDN) strives to better understand the human body and the ways in which different genes contribute to specific conditions. With research and clinical sites across the country, we are working to make groundbreaking advancements in the field of rare disease every day.
The UDN has funded multiple rounds of gene function studies to elucidate the biologic mechanisms of genetic variants identified in the UDN.
UDN Grand Rounds are open to the public. Presentations from UDN sites and cores describe the clinical phenotype and multidisciplinary, personalized diagnostic evaluation of one or more UDN participants. Students, trainees, advocates, and others are welcome to attend, ask questions, and offer insights on cases. CME credits are available at no charge for attendees.
The UDN Manual of Operations is a handbook that details the network’s research conduct and protocols in order to facilitate consistent adherence across all institutions participating in the study.
The Model Organisms Screening Center (MOSC) for the Undiagnosed Diseases Network (UDN) is a collaborative center with investigators from Baylor College of Medicine (BCM) and University of Oregon (UO). The MOSC allows for world-renowned experts in Drosophila (fruit fly) and Zebrafish genetics and biology to tackle undiagnosed diseases.
As we are an active research project, you can also read our latest publications, which come from some of the top minds in clinical research, DNA sequencing, and diagnostics.