Solving Medical Mysteries
Through Team Science


The Undiagnosed Disease Network (UDN) strives to better understand the human body and the ways in which different genes contribute to specific conditions. With research and clinical sites across the country, we are working to make groundbreaking advancements in the field of rare disease every day.

UDN Publications

As we are an active research project, you can also read our latest publications, which come from some of the top minds in clinical research, DNA sequencing, and diagnostics.

UDN Genes of Interest

Here, you can learn more about some of the genes we are studying.

UDN Model Organisms Screening Center

The Model Organisms Screening Center (MOSC) for the Undiagnosed Diseases Network (UDN) is a collaborative center with investigators from Baylor College of Medicine (BCM) and University of Oregon (UO). The MOSC allows for world-renowned experts in Drosophila (fruit fly) and Zebrafish genetics and biology to tackle undiagnosed diseases.

UDN Manual of Operations

The UDN Manual of Operations is a handbook that details the network’s research conduct and protocols in order to facilitate consistent adherence across all institutions participating in the study.