Funding Opportunities
Open Opportunities
Information: Clinical Research Support Core Subawards – October 2023
Application: https://redcap.wustl.edu/redcap/surveys/?s=7MDDDKA4DNRP3XLJ
Contact: dmccresearchcore@wustl.edu
Subawards will be funded to support X01, U01, and Affiliate UDN Sites and collaborators in: (1) site coordination or data submission, (2) confirming a diagnosis with metabolomics or gene function studies, and (3) obtaining pilot data to facilitate future, larger research studies.
Key Dates
Call for Subawards posted: August 3, 2023
Proposals due: October 1, 2023
Awards announced: November 1, 2023
Earliest start date: September 1, 2023
Project period: September 1, 2023-March 1, 2023
Submission Instructions
Final proposals must be submitted by 5:00 PM ET on October 1, 2023. Proposals received after this deadline will not be reviewed. Please adhere to the Format of Subawards described in the linked Clinical Research Support Core Subawards document.
Details about how to submit proposals will be added shortly.
Contact Information
If you have questions about the proposal requirements, please email fcole@wustl.edu.
Closed Opportunities
Gene Function Studies – January 2019
Gene Function Studies – September 2019
Gene Function Studies – September 2020
Funded Projects
| Institution(s) | Principal Investigator(s) | Project Title | Project Start Date |
|---|---|---|---|
| Baylor College of Medicine | Hugo J. Bellen, DVM, PhD | Understanding the role of IRF2BPL in neurological disease | July 1, 2019 |
| Baylor College of Medicine | Lindsay Burrage, MD, PhD | ER stress in TANGO2-related metabolic encephalopathy and arrhythmias | July 1, 2019 |
| University of Iowa | Lori Wallrath, PhD | Mechanisms of TMEM43 muscle disease | July 1, 2019 |
| University of Michigan | Paul C. Tang, MD, PhD | Elucidation of the Mechanism of Disease in a TAX1BP3 gene variant associated with human Arrhythmogenic Right Ventricular Cardiomyopathy | July 1, 2019 |
| University of Oregon | Monte Westerfield, PhD | Undiagnosed Diseases Network Gene Function Study MAST2 | July 1, 2019 |
| Washington University in St. Louis | Kristen Kroll, PhD | Using human pluripotent stem cell models to evaluate pathogenicity and define disease mechanisms for a ZNF292 variant found in a UDN participant | July 1, 2019 |
| The University of Texas MD Anderson Cancer Center | Swathi Arur, PhD | To understand the mechanism of action of the damaging DROSHA variant p.D1219G using C. elegans | July 1, 2020 |
| Baylor College of Medicine | Hugo J. Bellen, DVM, PhD | Exploring the role of WDR37 in a neurological syndrome with striking similarities to Schuurs-Hoeijmakers syndrome | July 1, 2020 |
| Washington University in St. Louis | John A. Cooper, MD, PhD | Using zebrafish as an animal model to evaluate pathogenicity and define disease mechanisms for a CARMIL3 variant (p.Gln928Glu) | July 1, 2020 |
| University of California, Davis | Daniel Starr, PhD | A humanized C. elegans model to study KLC4 kinesin light chain in disease | July 1, 2020 |
| University of Oregon | Monte Westerfield, PhD | Undiagnosed Diseases Network Gene Function Study PAPSS1 | July 1, 2020 |
| Baylor College of Medicine | Shinya Yamamoto, PhD | Exploring the molecular mechanisms of Glutaminase-related neurological diseases | July 1, 2020 |
| Baylor College of Medicine | Hugo J. Bellen, DVM, PhD and Scott Barish, PhD | Uncovering the molecular mechanisms of the chromatin remodeler BICRA in the nervous system | July 1, 2021 |
| Monash University | Robert Bryson-Richardson, PhD | Identifying the mechanism of, and therapies for, UBA5 epileptic encephalopathy | July 1, 2021 |
| The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. and Massachusetts General Hospital | Teresa Dunn, PhD and Florian Eichler, MD | The mechanistic basis of developmental delay due to mutations in SPTSSA | July 1, 2021 |
| Washington University in St. Louis | Lilianna Solnica-Krezel, PhD | Using zebrafish and human pluripotent stem cells to evaluate pathogenicity and define disease mechanisms for a ENY2 variant (p.K30Rfs*6) | July 1, 2021 |
| University of Alabama at Birmingham | Summer Thyme, PhD | Undiagnosed Diseases Network Gene Function Study NSD2 | July 1, 2021 |
| Rutgers University | Ching-On Wong, PhD | Delineating the signaling pathways associated with a disease-causing gain-of-function CLCN7 variant | July 1, 2021 |