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Participant 181


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Female, age 24 with chronic high blood pressure (hypertension) and autonomic nervous system dysfunction (dysautonomia)

Date of Report

Jun 03, 2021

Description

At 15 years old, the participant began experiencing high blood pressure (hypertension). Over the next 8 years, she was prescribed up to 6 different medications to regulate her high blood pressure. The participant was also found to have autonomic nervous system dysfunction (dysautonomia). She experienced side effects from high blood pressure (hypertensive retinopathy) as well.

The participant has a family history of high blood pressure on both sides of her family, but no one has severe and early-onset high blood pressure like she does.

Symptoms / Signs
  • High blood pressure (hypertension)
  • Autonomic nervous system dysfunction (abnormal autonomic nervous system physiology)
  • Low potassium (hypokalemia)
Current Treatments

Treatments for high blood pressure:

  • Amlodipine
  • Amiloride
  • Benazepril
  • Hydralazine
  • Propranolol
Prior Treatments
  • Florinef (fludrocortisone) – dysautonomia
  • Clonidine – high blood pressure
  • Guanfacine – high blood pressure
Considered treatments
  • Renal denervation
  • IVIg
Previously Considered Diagnoses
  • Dysautonomia syndromes (Riley-Day syndrome, Hereditary Sensory Autonomic Neuropathy Type III)
  • Monogenic hypertension syndromes
  • Pheochromocytoma
Other Photographs
Genetic Variants of Interest
Contact

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