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On this page, you will find information about a genetic change that was identified in a UDN participant.
Sharing information on this website is not a requirement of UDN participation. Only descriptions about participants who give explicit consent will appear here.
A change in the VSIG4 gene was identified in a male, age 7, with episodic fevers, food intolerance, projectile vomiting, and chronic constipation (read full description).
Jun 09, 2020
V-set and immunoglobulin domains-containing protein 4
The VSIG4 gene codes for a B7 family-related protein. It is expressed primarily on resting tissue macrophages and plays a role in inhibiting human T-cell responses and proliferation (Vogt et al., 2006).
A change in this gene was identified in a UDN participant. Research is underway to see if this change is causing symptoms in this participant.
Interested in learning more about this gene or sharing what you know? Contact us!